TR8™ Trait Regulation Platform
GeneNeer’s TR8™ Trait Regulation Platform is the next generation of gene-editing technology, facilitating crop trait expression on-demand and providing growers a powerful tool to fortify their produce against climate change, pests, viruses and other natural threats.
Gene Expression
with Precision and Control
The TR8™ Platform offers an effective method of introducing and controlling gene expression in response to external application of specific metabolites, with a high degree of specificity. As a result, GeneNeer’s TR8™ Platform has the potential to become an increasingly popular tool for a wide range of applications in genetic engineering (introducing foreign genetic material into a genome) and genome editing (modifying native trait expression within a given genome).






PREPARATIONS
GeneNeer tech.
locks the trait
(Inactive)






TRIGGER
Drought
and other stresses



APPLICATION
Apply inducer via
irrigation or spray






ACTIVATION
Trait is active
for 7-14 days



Induction to
“Unlock” Tolerance Traits
The technology is based on an RNA regulatory element (RE), designed by GeneNeer, which acts as an inducible gene system. The RE is a short, non-coding sequence, which, when spliced into the mRNA in an inducer-dependent manner, “locks” the targeted trait. By externally applying an inducer – the RE “unlocks” the trait, activating its desired gene and controlling its expression.
Advantages of Gene Editing Based on GeneNeer’s Superlines™
1
Competitive edge
Customers gain a tool for rapid development and innovation of enhanced crop seeds.
2
Precise control
Superlines’ RE can directly sense and respond to specific, nontoxic, low-cost metabolites.
3
Speed
Working from Superlines™ at the tissue-culture level eliminates the need for crossing or single-cell assays, thereby expediting response to impacts of climate change, and accelerating innovation.
4
Safety
GeneNeer’s technology enables complete control and extraction of the gene-editing machinery from the plant genome following editing, reducing the risk of off-target incidents.
5
Facilitating/Enabling
technology
In the case of potatoes and sweet potatoes, GeneNeer’s approach facilitates/enables gene-editing.
6
Stackable
Multiple traits may be added to a single Superline™.
7
Scalable
Superlines™ can be applied to a wide range of crops.
8
Modular
Superlines’ RE can be employed in a wide range of applications, allowing for a high degree of flexibility in controlling gene expression.
9
Empowering
Providing crop growers the right seeds helps them produce greater abundance and more profitable yields, while contributing to global food security.
7
Scalable
Superlines™ can be applied to a wide range of crops.
8
Modular
Superlines’ RE can be employed in a wide range of applications, allowing for a high degree of flexibility in controlling gene expression.
9
Empowering
Providing crop growers the right seeds helps them produce greater abundance and more profitable yields, while contributing to global food security.